New Human Papilloma Virus Isolated from Epidermodysplasia Verruciformis Lesions1
نویسندگان
چکیده
Human papilloma virus (HPV) was isolated from red plaques of a patient (N. F.) with epidermodysplasia verruciformis. Elec tron microscopic examination showed characteristic particles of papilloma virus as ¡cosahedrons about 45 nm in diameter. DNA was extracted from these particles, and closed-circular DNA (Form I) was purified by centrifugation in CsCI containing ethidium bromide. The molecular weight of the DNA was about 5.0 x 106. A physical map of the HPV DNA was constructed using several restriction enzymes. The restriction endonuclease cleavage pattern of the HPV DNA was different from those of other types of HPV reported thus far, suggesting that the isolate was a new, as yet unclassified, HPV.
منابع مشابه
New human papilloma virus isolated from epidermodysplasia verruciformis lesions.
Human papilloma virus (HPV) was isolated from red plaques of a patient (N. F.) with epidermodysplasia verruciformis. Electron microscopic examination showed characteristic particles of papilloma virus as icosahedrons about 45 nm in diameter. DNA was extracted from these particles, and closed-circular DNA (Form I) was purified by centrifugation in CsCl containing ethidium bromide. The molecular ...
متن کاملSebaceous Carcinoma of Inner Canthus of the Eye: Report of a Case
Introduction: This is to report a rare case of sebaceous carcinoma of inner cantus of the eye in relation with rare skin lesions of epidermodysplasia verruciformis. Epidermodysplasia verruciformis is a rare skin disease which is caused by human papilloma virus. Sebaceous carcinoma is a rare entity which is derived from sebaceous glands and to our best knowledge this is for the first time that w...
متن کاملEpidermodysplasia Verruciformis-like Skin Eruption in an HIV-positive Patient
Epidermodysplasia Verruciformis-like skin eruption is a rare syndrome that usually occurs in patients with immunodeficiency, predisposing them to infections with human papilloma β virus (HPV). We report here an HIV patient presenting with this syndrome.
متن کاملHuman papilloma virus 5-DNA in a carcinoma of an epidermodysplasia verruciformis patient infected with various human papillomavirus types.
An epidermodysplasia verruciformis patient suffering from generalized warts and a carcinoma at the forehead was found to be infected by at least six types and subtypes of human papillomaviruses. The central part of the carcinoma, however, harbored only human papillomavirus 5 DNA. The DNA persisted extrachromosomally in high genome copy number. In contrast to wart DNA preparations, a significant...
متن کاملAcquired epidermodysplasia verruciformis in a renal transplant recipient - Case report*
A 24-year-old male patient, who underwent kidney transplant six years ago due to Lupus nephritis, for the last two years presented asymptomatic erythematous scaly plaques on the abdomen and areas exposed to light. Post-transplantation immunosuppressive medications included prednisone, mycophenolate sodium and sirolimus. The histopathologic features were typical for epidermodysplasia verruciform...
متن کامل